Searchable abstracts of presentations at key conferences in endocrinology

ea0032p499 | Endocrine disruptors | ECE2013

Tributyltin changes the thyroid gland morphology of male rats

Pereira Paula Rodrigues , Mattos Romulo Medina de , Palmero Celia Yelimar , Fortunato Rodrigo , Gracelli Jones Bernardes , Carvalho Denise Pires de , Nasciutti Luiz Eurico , Miranda-Alves Leandro

Triorganotins, such as tributyltin (TBT), are environmental contaminants commonly found in antifouling paints that are used on the ships and other vessels. Unfortunately, these chemical are also suspected to cause endocrine-disrupting effects in mammals, due in part to their possible transfer through marine food chains and to the consumption of contaminated seafood. The importance of triorganotins as environmental endocrine disruptors in different animal models is well known; ...

ea0026p292 | Pituitary | ECE2011

Carotenoids inhibits cell proliferation, arrest cell cycle and induces apoptosis in pituitary tumor cells

Haddad Natalia , Tedoro Anderson Junger , Soares Nathalia da Costa Pereira , Oliveira Felipe Leite , Borojevic Radovan , Nasciutti Luiz Eurico , Alves Leandro Miranda

Pituitary adenomas account for ~10% of intracranial tumors and result in morbidity due to both altered hormonal patterns as well as side effects of therapy. Currently, great attention has been given to preventive strategies, and in this context, the use of functional foods with chemopreventive compounds appears to contribute much in this process. Among these substances, we highlight the consumption of carotenoids is associated with reduced risk of chronic diseases including ca...